Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | BCDIN3D | Q7Z5W3 | 3/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898746 | 0.91 | TOP2A (0.53) | BCDIN3DSLC2A1USP2CYP1A2CYP3A4 | |
| SCHEMBL8901507 | 0.89 | TRIM58 (0.53) | BCDIN3DUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8898099 | 0.89 | CYP1A2 (0.55) | TLR9USP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8890605 | 0.88 | VCP (0.44) | TLR9BCDIN3DSLC2A1USP2KAT2B | |
| SCHEMBL8898278 | 0.84 | SOS1 (0.52) | BCDIN3DTRIM58PDE5ACASP6TLR7 | |
| SCHEMBL8901747 | 0.82 | TAAR1 (0.56) | SLC2A1USP2TLR7APP | |
| SCHEMBL8898399 | 0.81 | HTR3E (0.53) | CYP1A2CYP3A4CYP2D6HRH4HSD17B10 | |
| SCHEMBL8898526 | 0.81 | CYP1A2 (0.50) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL8898947 | 0.81 | TLR9 (0.51) | TLR9TRIM58PDE5AFLT3CASP6 | |
| SCHEMBL23723480 | 0.81 | RAD52 (0.63) | TLR9SLC2A1HRH4PDE5ACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |