Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM58 | Q8NG06 | 3/20 | 0.53 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898746 | 0.90 | TOP2A (0.53) | TRIM58BCDIN3DAPPTLR7CYP1A2 | |
| SCHEMBL8890645 | 0.89 | TLR9 (0.47) | TRIM58BCDIN3DAPPTLR7CYP1A2 | |
| SCHEMBL8898099 | 0.88 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6ALOX15USP2 | |
| SCHEMBL8901492 | 0.88 | TRIM58 (0.49) | TRIM58APPACHEACP1 | |
| SCHEMBL8898278 | 0.83 | SOS1 (0.52) | TRIM58BCDIN3DAPPTLR7SOS1 | |
| SCHEMBL8901747 | 0.81 | TAAR1 (0.56) | APPTLR7USP2SOS1TSHR | |
| SCHEMBL8898526 | 0.79 | CYP1A2 (0.50) | TRIM58APPTLR7CYP1A2CYP3A4 | |
| SCHEMBL8898947 | 0.79 | TLR9 (0.51) | TRIM58APPTLR7SOS1BCHE | |
| SCHEMBL8898730 | 0.78 | ACP1 (0.52) | APPACHETOP2AACP1 | |
| SCHEMBL8889922 | 0.78 | NPY5R (0.49) | TRIM58APPTLR7SOS1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |