Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PGK1 | P00558 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898278 | 0.91 | SOS1 (0.52) | RAD52MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL8901739 | 0.87 | TAAR1 (0.52) | TAAR1HTTPOLBSMN1; SMN2RAD52 | |
| SCHEMBL8899155 | 0.86 | TRIM58 (0.57) | POLBRAD52KMT2AALDH1A1SLC2A1 | |
| SCHEMBL8907323 | 0.86 | TRIM58 (0.57) | POLBRAD52KMT2AALDH1A1SLC2A1 | |
| SCHEMBL8898526 | 0.85 | CYP1A2 (0.50) | MAPTKMT2AKDM4EALDH1A1TLR7 | |
| SCHEMBL8898947 | 0.85 | TLR9 (0.51) | POLBRAD52GAAALDH1A1TLR7 | |
| SCHEMBL8889922 | 0.84 | NPY5R (0.49) | RAD52MAPTALDH1A1TLR7APP | |
| SCHEMBL8890983 | 0.84 | TLR7 (0.45) | RAD52MAPTALDH1A1TLR7APP | |
| SCHEMBL8890083 | 0.84 | POLB (0.55) | POLBGAASLC2A1APPSOS1 | |
| SCHEMBL8908343 | 0.84 | POLB (0.55) | POLBGAASLC2A1APPSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |