Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1724987 | 0.82 | HCAR3 (0.52) | HCAR3MAPTALDH1A1PKMCDK2 | |
| SCHEMBL9835504 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1PKMNPC1RAB9A | |
| SCHEMBL9835516 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1PKMNPC1RAB9A | |
| SCHEMBL14559830 | 0.79 | PKM (0.55) | MAPTALDH1A1PKMNPC1LMNA | |
| SCHEMBL8902085 | 0.79 | CISD1 (0.50) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL2700000 | 0.79 | LMNA (0.64) | HCAR3MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL12963701 | 0.78 | KDM4E (0.60) | MAPTALDH1A1KDM4EAKR1C3AKR1C2 | |
| SCHEMBL5095253 | 0.77 | PKM (0.54) | MAPTALDH1A1PKMCDK2KDM4E | |
| SCHEMBL2903458 | 0.77 | PKM (0.58) | MAPTALDH1A1PKMNPC1LMNA | |
| SCHEMBL8902448 | 0.76 | AKR1C3 (0.46) | MAPTALDH1A1PKMLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |