Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.54 |
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 2/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899558 | 0.85 | ACKR3 (0.53) | HTR7HTR6CCR1SLC6A9NPY5R | |
| SCHEMBL24069080 | 0.84 | HTR7 (0.58) | HTR7HTR6CCR1P2RX7SLC6A9 | |
| Hydrochloric Acid SCHEMBL11101542 | 0.84 | ALOX15 (0.64) | HTR7HTR6CCR1SLC6A9NPY5R | |
| Hydrochloric Acid SCHEMBL11101388 | 0.83 | SLC6A9 (0.63) | HTR7HTR6CCR1SLC6A9NPY5R | |
| SCHEMBL24070221 | 0.81 | HTR7 (0.61) | HTR7HTR6CCR1NPY5RDRD2 | |
| SCHEMBL27900155 | 0.79 | SCN1A (0.49) | HTR7CCR1P2RX7SLC6A9NPY5R | |
| SCHEMBL27917809 | 0.79 | NPY5R (0.58) | NPY5RALDH1A1NPY1R | |
| SCHEMBL24070145 | 0.78 | NPY5R (0.60) | HTR7HTR6NPY5RDRD2HTR2A | |
| SCHEMBL24069068 | 0.78 | HTR7 (0.71) | HTR7HTR6CCR1NPY5RDRD2 | |
| SCHEMBL11101165 | 0.78 | HTR7 (0.67) | HTR7HTR6CCR1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020820-A1 | HETEROARYL COMPOUNDS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |