SCHEMBL24070221

SCHEMBL24070221

O=S(=O)(NCCN1CCC(c2ccccc2)CC1)c1cccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 5/20 0.61
HTR6 P50406 4/20 0.61
DRD2 P14416 3/20 0.61
HTR2A P28223 3/20 0.61
BCHE P06276 1/20 0.60
NPY5R Q15761 11/20 0.58
CARM1 Q86X55 1/20 0.53
PRMT6 Q96LA8 1/20 0.53
NPY1R P25929 8/20 0.53
CCR1 P32246 1/20 0.50
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25759707 0.93 BCHE (0.63) HTR7HTR6DRD2HTR2ABCHE
SCHEMBL24070145 0.85 NPY5R (0.60) HTR7HTR6DRD2HTR2ANPY5R
Hydrochloric Acid SCHEMBL11101542 0.84 ALOX15 (0.64) HTR7HTR6DRD2HTR2ANPY5R
Hydrochloric Acid SCHEMBL11101388 0.83 SLC6A9 (0.63) HTR7HTR6DRD2HTR2ANPY5R
SCHEMBL24069080 0.82 HTR7 (0.58) HTR7HTR6DRD2HTR2ABCHE
SCHEMBL7461976 0.81 BCHE (0.55) HTR7HTR6DRD2HTR2ABCHE
SCHEMBL8900712 0.81 HTR7 (0.54) HTR7HTR6DRD2HTR2ANPY5R
SCHEMBL25758471 0.80 HTR7 (0.60) HTR7HTR6DRD2HTR2ABCHE
SCHEMBL25759673 0.79 DRD4 (0.57) HTR7HTR6DRD2HTR2ANPY5R
SCHEMBL24070176 0.78 CARM1 (0.50) HTR7HTR6DRD2HTR2ABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157124-A Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-23 CN claimed
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 US disclosed
CN-116157124-A Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-23 CN disclosed
EP-4159718-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS Daegu-Gyeongbuk Medical Innovation Foundation (KR) 2023-04-05 EP disclosed
WO-2021241875-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS 재단법인 대구경북첨단의료산업진흥재단 2021-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS SLC6A2, SLC6A3, SLC6A4 HTR7 79/4885HTR6 47/4885DRD2 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.