Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902897 | 0.88 | ELANE (0.34) | ELANEBRD4KMT2ACASR | |
| SCHEMBL8902356 | 0.86 | HEXA (0.38) | ELANEBRD4KMT2ACASRKDM4E | |
| SCHEMBL8901663 | 0.84 | KDM4E (0.33) | ELANEBRD4KMT2AUSP2ALDH1A1 | |
| SCHEMBL8901653 | 0.84 | PDE5A (0.33) | ELANEBRD4USP2CASRNR1I2 | |
| SCHEMBL11965004 | 0.84 | PDE4A (0.41) | ELANEBRD4LMNANPSR1KDM4E | |
| SCHEMBL8903480 | 0.83 | GABRA1 (0.35) | ELANEBRD4KMT2ACASR | |
| SCHEMBL8900869 | 0.82 | PDE5A (0.40) | ELANEBRD4LMNAMAPK14NPSR1 | |
| SCHEMBL11965006 | 0.82 | PTGS2 (0.40) | BRD4LMNANPSR1ALDH1A1POLB | |
| SCHEMBL8901048 | 0.81 | POLB (0.47) | LMNAKMT2ANPSR1ALDH1A1POLB | |
| SCHEMBL12603544 | 0.79 | MAPT (0.39) | BRD4LMNAKMT2AUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188008-B2 | Herbicidally and insecticidally active 4-phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX4, PRDX1 | ELANE 3397/4885BRD4 1433/4885LMNA 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.