Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900862 | 0.88 | ELANE (0.35) | ELANEBRD4CASRKMT2A | |
| SCHEMBL11965018 | 0.86 | MAPT (0.36) | ELANEDHODHBRD4TACR1SLC22A12 | |
| SCHEMBL8901663 | 0.85 | KDM4E (0.33) | ELANEBRD4KMT2AMEN1 | |
| SCHEMBL8902356 | 0.84 | HEXA (0.38) | ELANEBRD4SLC22A12CASRKMT2A | |
| SCHEMBL8902940 | 0.84 | METAP2 (0.38) | ELANEDHODHBRD4TACR1SLC22A12 | |
| SCHEMBL11965014 | 0.84 | PTGS2 (0.38) | ELANEBRD4TACR1GCGRKMT2A | |
| SCHEMBL8902971 | 0.83 | PDE5A (0.44) | TACR1SLC22A12KMT2AIDO1TDO2 | |
| SCHEMBL8901653 | 0.82 | PDE5A (0.33) | ELANEBRD4CASR | |
| SCHEMBL8903480 | 0.81 | GABRA1 (0.35) | ELANEBRD4CASRKMT2AMEN1 | |
| SCHEMBL8900968 | 0.81 | ALDH1A1 (0.40) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188008-B2 | Herbicidally and insecticidally active 4-phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX4, PRDX1 | ELANE 3397/4885DHODH 2089/4885BRD4 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.