Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10538919 | 0.83 | GAA (0.50) | HSD11B1GAAPOLBALDH1A1MAPT | |
| SCHEMBL8356461 | 0.77 | LMNA (0.45) | HSD11B1GAAPOLBKMT2AALDH1A1 | |
| SCHEMBL7051694 | 0.73 | HTR6 (0.40) | GAAKMT2AALDH1A1MAPTHTR6 | |
| SCHEMBL27258081 | 0.72 | RAB9A (0.47) | HSD11B1KMT2AALDH1A1NR3C2CES2 | |
| SCHEMBL9172146 | 0.72 | NPSR1 (0.44) | HSD11B1GAAPOLBKMT2AALDH1A1 | |
| SCHEMBL6265807 | 0.70 | HTR6 (0.60) | GAAKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL28326313 | 0.69 | HTR6 (0.58) | GAAKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8916208 | 0.68 | HTR6 (0.44) | GAAKMT2AALDH1A1MAPTHTR6 | |
| SCHEMBL8621263 | 0.68 | AKR1C3 (0.52) | GAAPOLBKMT2AALDH1A1MAPT | |
| SCHEMBL4600284 | 0.68 | EGFR (0.39) | GAAPOLBKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797774-A1 | MULTILAYER ANALYTICAL ELEMENT | 2860601 Canada Inc. (CN) | 1997-10-01 | — | — | EP | claimed |
| WO-1996018898-A1 | MULTILAYER ANALYTICAL ELEMENT | 2860601 CANADA INC. (CA) | 1996-06-20 | — | — | WO | claimed |