Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | CASR | P41180 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901050 | 0.93 | ADRA1A (0.40) | ADRA1AHRH1ADRA1BHRH3CASR | |
| SCHEMBL8903058 | 0.92 | ALDH1A1 (0.40) | ADRA1AHRH1ADRA1BTP53 | |
| SCHEMBL8902466 | 0.91 | CASR (0.42) | CASRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8901247 | 0.88 | ADRA1A (0.38) | ADRA1AHRH1ADRA1BHRH3CASR | |
| SCHEMBL8902121 | 0.87 | MAPT (0.36) | ADRA1AHRH1ADRA1BHRH3MAPT | |
| SCHEMBL8901068 | 0.87 | TP53 (0.40) | ADRA1AHRH1ADRA1BCASRTRPA1 | |
| SCHEMBL11965017 | 0.87 | PTGS2 (0.38) | — | |
| SCHEMBL8902645 | 0.85 | TACR1 (0.41) | CASP3CASP7 | |
| SCHEMBL8901251 | 0.84 | CASR (0.37) | ADRA1AHRH1ADRA1BCASRTRPA1 | |
| SCHEMBL8901216 | 0.84 | CASR (0.44) | CASRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188008-B2 | Herbicidally and insecticidally active 4-phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX4, PRDX1 | ADRA1A 353/4885HRH1 1824/4885ADRA1B 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.