Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18297576 | 0.76 | HTR1A (0.38) | ADRA2AHTR1ASLC6A2SLC6A4TSHR | |
| SCHEMBL4104527 | 0.76 | HPGD (0.38) | ADRA2AHTR1ASLC6A2SLC6A4TSHR | |
| SCHEMBL7526110 | 0.76 | BCL2L1 (0.48) | ADRA2AHTR1ASLC6A2SLC6A4TSHR | |
| SCHEMBL23987301 | 0.76 | HTR1A (0.39) | ADRA2AHTR1ASLC6A2SLC6A4TSHR | |
| SCHEMBL8581327 | 0.76 | HTR1A (0.41) | ADRA2AHTR1ASLC6A2SLC6A4TSHR | |
| SCHEMBL23979971 | 0.76 | HTR1A (0.38) | ADRA2AHTR1ASLC6A2SLC6A4TSHR | |
| SCHEMBL23987322 | 0.73 | HTR2A (0.34) | PNMTHTR2CHTR2AHTR2B | |
| SCHEMBL28446259 | 0.72 | RYR2 (0.53) | ADRA2AADRA2BADRA2CPNMTHTR2C | |
| SCHEMBL9409715 | 0.72 | HTR1A (0.41) | ADRA2AHTR1ASLC6A2SLC6A4TSHR | |
| SCHEMBL7426602 | 0.72 | ALDH1A1 (0.40) | ADRA2AHTR1ASLC6A2SLC6A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119384413-A | Anilino-pyrazole derivatives, compositions and methods thereof | 昂胜医药有限公司 | 2025-01-28 | — | — | CN | disclosed |
| EP-0810227-A1 | ISOXAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |