SCHEMBL8901433

SCHEMBL8901433

CCc1cn(-c2cc(C(=O)O)ccc2NC(C)=O)c(N)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
KDM4E B2RXH2 6/20 0.44
MAPT P10636 6/20 0.44
GAA P10253 5/20 0.44
HPGD P15428 4/20 0.44
THRB P10828 2/20 0.44
GFER P55789 2/20 0.44
HTT P42858 1/20 0.44
PLEC Q15149 1/20 0.44
NEU3 Q9UQ49 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
RAB9A P51151 3/20 0.39
PTGER4 P35408 1/20 0.38
NPC1 O15118 3/20 0.36
MAPK1 P28482 1/20 0.35
LMNA P02545 1/20 0.35
BRD4 O60885 2/20 0.35
EP300 Q09472 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8901022 0.81 ADORA3 (0.44) ALDH1A1KDM4EMAPTGAAHPGD
SCHEMBL8891817 0.79 ADORA3 (0.44) ALDH1A1KDM4EMAPTGAAHPGD
SCHEMBL8891755 0.78 PTGFR (0.41) ALDH1A1KDM4EMAPTGAAHPGD
SCHEMBL8891736 0.78 ADORA3 (0.46) ALDH1A1KDM4EMAPTNEU3SMN1; SMN2
SCHEMBL8892526 0.76 ADORA3 (0.47) ALDH1A1KDM4EMAPTGAAHPGD
SCHEMBL8900474 0.76 NEU3 (0.47) ALDH1A1KDM4EMAPTGAAHPGD
Trifluoroacetic Acid SCHEMBL8901207 0.76 ALDH1A1 (0.40) ALDH1A1KDM4EMAPTGAAHPGD
SCHEMBL8891085 0.76 TLR8 (0.41) MAPTNEU3CREBBPPTGFR
SCHEMBL8900520 0.75 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTGAAHPGD
Trifluoroacetic Acid SCHEMBL8894608 0.74 ADORA3 (0.40) ALDH1A1KDM4EMAPTGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997033872-A1 ANTI-VIRAL 4-ACYLAMINO-3-[IMIDAZOL-I-YL]-BENZOIC ACID DERIVATIVES BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 1997-09-18 WO disclosed