Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | TDO2 | P48775 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377784 | 0.86 | MAPT (0.50) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5186834 | 0.85 | CASP6 (0.60) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10945384 | 0.85 | G6PD (0.60) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10944706 | 0.85 | MAPT (0.59) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4728660 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11543737 | 0.83 | MAPT (0.47) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11973643 | 0.82 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10943147 | 0.82 | CTSB (0.47) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4729833 | 0.81 | KDM4E (0.44) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2469901 | 0.81 | ALDH1A1 (0.61) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997006161-A1 | ANTICOCCIDIAL 8-AMINOQUINOLINE DERIVATIVES | PFIZER LIMITED (GB) | 1997-02-20 | — | — | WO | disclosed |