Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901817 | 0.77 | HTT (0.48) | LMNAMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL521069 | 0.69 | MAPT (0.57) | LMNAMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL9827937 | 0.67 | KMT2A (0.58) | LMNAMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL9710536 | 0.66 | ALDH1A1 (0.57) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL10996751 | 0.66 | MAPT (0.53) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8901821 | 0.65 | L3MBTL1 (0.39) | LMNAMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL8529815 | 0.64 | ADRA1A (0.46) | ALDH1A1KDM4E | |
| SCHEMBL398701 | 0.64 | LMNA (0.73) | LMNAMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL9710538 | 0.64 | MAPT (0.55) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL27874614 | 0.64 | ALDH1A1 (0.55) | LMNAMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |
| EP-0533744-A1 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |