Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.52 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TK2 | O00142 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908320 | 0.82 | TYMP (0.43) | TK1HPGDTK2MAPK1 | |
| SCHEMBL8908130 | 0.78 | CHRNB2 (0.43) | MEN1KMT2AMAPK1CHRNB2CHRNA5 | |
| SCHEMBL10569472 | 0.75 | TK1 (0.59) | TK1RNASE1HPGDTK2MAPK1 | |
| SCHEMBL8909572 | 0.75 | CHRNB2 (0.36) | MEN1KMT2ACHRNB2CHRNA5CHRNA7 | |
| SCHEMBL8900287 | 0.75 | EP300 (0.38) | MEN1KMT2ACHRNB2CHRNA5CHRNA7 | |
| SCHEMBL10571570 | 0.72 | TK1 (0.58) | TK1RNASE1HPGDTK2MEN1 | |
| SCHEMBL10571564 | 0.72 | TK1 (0.58) | TK1RNASE1HPGDTK2MEN1 | |
| SCHEMBL8907404 | 0.72 | EGFR (0.49) | HPGD | |
| SCHEMBL8707821 | 0.70 | TK1 (0.64) | TK1RNASE1HPGDTK2MAPK1 | |
| SCHEMBL14580373 | 0.70 | RNASE1 (0.57) | TK1RNASE1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | claimed |
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | disclosed |