Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901990 | 0.78 | TK1 (0.52) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL8909572 | 0.78 | CHRNB2 (0.36) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL8908293 | 0.77 | CHRNB2 (0.47) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL8900287 | 0.76 | EP300 (0.38) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL8908336 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL8907404 | 0.74 | EGFR (0.49) | SMN1; SMN2 | |
| SCHEMBL1021591 | 0.68 | TDP1 (0.52) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL532785 | 0.67 | CARM1 (0.61) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL8447322 | 0.67 | CARM1 (0.61) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL9067211 | 0.67 | CHRNB2 (0.44) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | disclosed |