SCHEMBL89023

SCHEMBL89023

O=C1Cc2ccccc2CN1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
HSD17B10 Q99714 1/20 0.56
AHR P35869 2/20 0.50
PDK2 Q15119 1/20 0.50
CYP1A2 P05177 1/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
TDP2 O95551 2/20 0.47
CASP3 P42574 1/20 0.47
CASP7 P55210 1/20 0.47
CASP9 P55211 1/20 0.47
CASP6 P55212 1/20 0.47
CASP8 Q14790 1/20 0.47
MAP3K14 Q99558 1/20 0.47
CYP2A6 P11509 1/20 0.43
ALDH1A1 P00352 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
TYRO3 Q06418 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4317475 0.84 CYP2A6 (0.44) ALOX15HSD17B10AHRPDK2CYP1A2
SCHEMBL2062062 0.79 NPC1 (0.52) ALOX15HSD17B10AHRPDK2CA12
SCHEMBL25405402 0.78 CLK4 (0.60) CYP1A2TDP2ALDH1A1TYRO3NTRK2
SCHEMBL2061125 0.77 PARP10 (0.53) AHRPDK2CYP1A2TDP2CASP3
SCHEMBL2313287 0.77 AHR (0.70) AHRPDK2CYP1A2TDP2CASP3
SCHEMBL14061414 0.77 CA12 (0.56) ALOX15HSD17B10AHRPDK2CYP1A2
SCHEMBL17376995 0.74 CHRNB2 (0.42) CYP1A2TDP2
SCHEMBL30225261 0.74 CHRNB2 (0.42) CYP1A2TDP2
SCHEMBL23975908 0.74 CHRNB2 (0.42) CYP1A2TDP2
SCHEMBL7596114 0.74 OR51E2 (0.48) AHRPDK2CYP1A2TDP2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678634-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF Haihe Biopharma Co., Ltd. (CN) 2026-01-14 EP claimed
EP-4611899-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP claimed
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-14 US claimed
WO-2024183793-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF 上海海和药物研究开发股份有限公司 2024-09-12 WO claimed
US-20240182460-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PETRA PHARMA CORPORATION 2024-06-06 US claimed
WO-2024097172-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PETRA PHARMA CORPORATION (US) 2024-05-10 WO claimed
US-20180277766-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE ORGANIC LIGHT EMITTING DIODE HAVING HOST MATRIX POLARITY CO-DOPING DOW GLOBAL TECHNOLOGIES LLC 2018-09-27 US claimed
US-20090233910-A1 Npy antagonists, preparation and uses CEREP (FR) 2009-09-17 US claimed
EP-1963273-A2 SUBSTITUTED ISOQUINOLINE-1,3(2H,4H)-DIONES, 1-THIOXO-1,4-DIHYDRO-2H-ISOQUINOLINE-3-ONES AND 1,4-DIHYDRO-3(2H)-ISOQUINOLONES AND USE THEREOF AS KINASE INHIBITORS Wyeth a Corporation of the State of Delaware (US) 2008-09-03 EP claimed
US-20080085890-A1 Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo-1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihydro-3 (2H)-isoquinolones and methods of use thereof WYETH (US) 2008-04-10 US claimed
WO-2007075783-A2 SUBSTITUTED ISOQUINOLINE-1,3(2H,4H)-DIONES, 1-THIOXO-1,4-DIHYDRO-2H-ISOQUINOLINE-3-ONES AND 1,4-DIHYDRO-3(2H)-ISOQUINOLONES AND USE THEREOF AS KINASE INHIBITOR WYETH (US) 2007-07-05 WO claimed
EP-0789577-B1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORP (US) 2003-03-12 EP claimed
EP-0628030-B1 2,3,4,5-TETRAHYDRO-1H --3-BENZAZEPINES HAVING ANTI-PSYCHOTIC ACTIVITY, AND SYNTHESIS OF $g(a)-SUBSTITUTED-ARYLACETAMIDES SCHERING CORP (US) 2002-12-11 EP claimed
US-5530125-A REACTING ARYLACETAMIDE WITH STRONG BASE IN INERT APROTIC SOLVENT, THEN WITH SPECIFIED REACTANT IN PRESENCE OF TRANSITION METAL CATALYST TO ADD ALPHA-SUBSTITUENT,REDUCING TO AMINE SCHERING CORPORTION (US) 1996-06-25 US claimed
EP-0628030-A1 2,3,4,5-TETRAHYDRO-1H --3-BENZAZEPINES HAVING ANTI-PSYCHOTIC ACTIVITY, AND SYNTHESIS OF $g(a)-SUBSTITUTED-ARYLACETAMIDES SCHERING CORPORATION (US) 1994-12-14 EP claimed
WO-1993016997-A1 2,3,4,5-TETRAHYDRO-1H^_-3-BENZAZEPINES HAVING ANTI-PSYCHOTIC ACTIVITY, AND SYNTHESIS OF α-SUBSTITUTED-ARYLACETAMIDES SCHERING CORPORATION (US) 1993-09-02 WO claimed
WO-2026107076-A1 CDK2 INHIBITOR COMPOUNDS ALEKSIA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
EP-4722195-A1 PH-SENSITIVE CATIONIC LIPID AND LIPID NANOPARTICLES National University Corporation Hokkaido University (JP) 2026-04-08 EP disclosed
US-3946018-A ANTICONVULSANTS EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1976-03-23 US disclosed
US-3946018-A ANTICONVULSANTS EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090233910-A1 Npy antagonists, preparation and uses NPY1R, NPY5R, NPY2R ALOX15 1766/4885HSD17B10 3929/4885AHR 381/4885
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 ALOX15 1362/4885HSD17B10 1094/4885AHR 4252/4885
US-20080085890-A1 Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo-1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihydro-3 (2H)-isoquinolones and methods of use thereof SULT1E1, RECQL, HAX1 ALOX15 2954/4885HSD17B10 1969/4885AHR 1357/4885
US-20240182460-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PIK3CA, PIK3R4, PIK3R5 ALOX15 2996/4885HSD17B10 466/4885AHR 1341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.