Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 5/20 | 0.60 |
| ▸ | CTSL | P07711 | 5/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232948 | 0.87 | ABCB1 (0.57) | CTSVCTSLABCB1MEN1KMT2A | |
| SCHEMBL2722340 | 0.86 | CTSV (0.60) | CTSVCTSLABCB1MEN1KMT2A | |
| SCHEMBL159283 | 0.85 | CTSV (0.60) | CTSVCTSLABCB1MEN1KMT2A | |
| SCHEMBL873861 | 0.85 | CTSV (0.60) | CTSVCTSLABCB1MEN1KMT2A | |
| SCHEMBL28257932 | 0.84 | CTSV (0.63) | CTSVCTSLABCB1MEN1KMT2A | |
| SCHEMBL31756984 | 0.83 | MEN1 (0.56) | CTSVCTSLABCB1MEN1KMT2A | |
| SCHEMBL10585706 | 0.83 | MEN1 (0.56) | CTSVCTSLABCB1MEN1KMT2A | |
| SCHEMBL5095253 | 0.82 | PKM (0.54) | MAPTALDH1A1 | |
| SCHEMBL7116860 | 0.82 | POLB (0.56) | CTSVCTSLABCB1MEN1KMT2A | |
| SCHEMBL6820117 | 0.82 | HTR1A (0.51) | CTSVCTSLABCB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |