Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | FABP1 | P07148 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903449 | 1.00 | VCAM1 (0.39) | VCAM1PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL8902908 | 0.88 | PTGS1 (0.38) | PTGS2PTGS1 | |
| SCHEMBL8901651 | 0.88 | PTGS1 (0.38) | PTGS2PTGS1 | |
| SCHEMBL8903186 | 0.84 | CDK1 (0.41) | VCAM1LTB4RPTGS2 | |
| SCHEMBL8903452 | 0.84 | CDK1 (0.41) | VCAM1LTB4RPTGS2 | |
| SCHEMBL8902498 | 0.81 | CDK1 (0.38) | PTGS2PTGS1 | |
| SCHEMBL8903387 | 0.80 | CDK1 (0.39) | VCAM1PTGS2 | |
| SCHEMBL8901819 | 0.80 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8903375 | 0.80 | RXRA (0.43) | — | |
| SCHEMBL8902845 | 0.75 | CA1 (0.43) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602140-A | CAUSED BY LEUKOCYTES | JAPAN ENERGY CORPORATION (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0675124-A2 | Purine derivatives and suppressants for inflammatory diseases | JAPAN ENERGY CORPORATION (JP) | 1995-10-04 | — | — | EP | disclosed |