Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901819 | 0.84 | PTGS2 (0.46) | CA1CA2PTGS1PTGS2NISCH | |
| SCHEMBL8902908 | 0.78 | PTGS1 (0.38) | CA1CA2PTGS1PTGS2 | |
| SCHEMBL8901651 | 0.78 | PTGS1 (0.38) | CA1CA2PTGS1PTGS2 | |
| SCHEMBL8902849 | 0.78 | CA1 (0.43) | CA1CA2PTGS1PTGS2 | |
| SCHEMBL8903375 | 0.76 | RXRA (0.43) | — | |
| SCHEMBL8902498 | 0.75 | CDK1 (0.38) | PTGS1PTGS2 | |
| SCHEMBL8903449 | 0.75 | VCAM1 (0.39) | PTGS1PTGS2 | |
| SCHEMBL8903180 | 0.75 | VCAM1 (0.39) | PTGS1PTGS2 | |
| SCHEMBL2470646 | 0.75 | CA2 (0.70) | CA1CA2PTGS1PTGS2 | |
| SCHEMBL16474223 | 0.74 | ADORA3 (0.47) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602140-A | CAUSED BY LEUKOCYTES | JAPAN ENERGY CORPORATION (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0675124-A2 | Purine derivatives and suppressants for inflammatory diseases | JAPAN ENERGY CORPORATION (JP) | 1995-10-04 | — | — | EP | disclosed |