SCHEMBL890358

SCHEMBL890358

F[C](F)c1ccccc1[C](F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
ALOX15 P16050 3/20 0.42
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
HPGD P15428 5/20 0.35
KDM4E B2RXH2 4/20 0.35
MAPT P10636 4/20 0.35
CA12 O43570 3/20 0.35
CA2 P00918 3/20 0.35
CA4 P22748 3/20 0.35
CA14 Q9ULX7 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
HSD17B10 Q99714 3/20 0.35
CA3 P07451 2/20 0.35
NPC1 O15118 2/20 0.35
POLB P06746 2/20 0.35
GMNN O75496 1/20 0.35
EGFR P00533 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL489916 0.81 CES2 (0.59) ALDH1A1ALOX15CES2CES1HPGD
SCHEMBL17474473 0.81 HPGD (0.52) ALDH1A1ALOX15HPGDKDM4EMAPT
SCHEMBL9989507 0.78 CES2 (0.56) ALDH1A1CES2CES1HPGDPOLB
SCHEMBL17330507 0.78 ACHE (0.47) HPGDSMN1; SMN2TSHRBCHE
SCHEMBL3245130 0.74 NR4A1 (0.58) ALDH1A1ALOX15HPGDKDM4EMAPT
SCHEMBL17331003 0.73 GABRA1 (0.46) ALDH1A1HPGDMAPTGAATSHR
SCHEMBL28535087 0.73 ALDH1A1 (0.35) ALDH1A1ALOX15CES2CES1HPGD
SCHEMBL1705501 0.73 CA1 (0.55) CA12CA2CA4CA14SMN1; SMN2
SCHEMBL726749 0.72 ALDH1A1 (0.38) ALDH1A1ALOX15CES2CES1HPGD
SCHEMBL103048 0.72 ALDH1A1 (0.53) ALDH1A1ALOX15CES2CES1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278138-B2 Resistive memory device and method of fabricating the same ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2012-10-02 US disclosed
US-20110272661-A1 RESISTIVE MEMORY DEVICE AND METHOD OF FABRICATING THE SAME ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2011-11-10 US disclosed