Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CDC42 | P60953 | 1/20 | 0.45 |
| ▸ | RAC1 | P63000 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564255 | 0.77 | LMNA (0.42) | TSHRCYP1A2LMNAMAPTCYP2C9 | |
| SCHEMBL1726389 | 0.76 | MEN1 (0.61) | PTGS2TSHRCYP1A2LMNA | |
| SCHEMBL4016088 | 0.74 | MEN1 (0.59) | PTGS2TSHRCYP1A2LMNA | |
| SCHEMBL3772672 | 0.74 | MEN1 (0.59) | PTGS2TSHRCYP1A2LMNA | |
| SCHEMBL2326546 | 0.73 | MEN1 (0.58) | PTGS2TSHRCYP1A2LMNA | |
| SCHEMBL9568576 | 0.72 | HTT (0.38) | TSHRCYP1A2LMNAMAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL27504393 | 0.72 | MEN1 (0.56) | PTGS2TSHRCYP1A2LMNA | |
| SCHEMBL9615906 | 0.70 | HTT (0.43) | TSHRLMNAMAPT | |
| SCHEMBL14566923 | 0.70 | AKR1C3 (0.49) | AKR1C3AKR1C2ABCB11TSHRCYP2C9 | |
| SCHEMBL8586535 | 0.70 | HTT (0.39) | TSHRCYP1A2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860169-B1 | Method for obtaining novel derivatives of naphtalene for the in vivo diagnosis of Alzheimer's disease | CENTRO DE NEUROCIENCIAS DE CUBA (CU) | 2018-08-29 | — | — | EP | disclosed |
| EP-2860169-A2 | Method for obtaining novel derivatives of naphtalene for the in vivo diagnosis of Alzheimer's disease | Centro De Neurociencias De Cuba (CU) | 2015-04-15 | — | — | EP | disclosed |
| EP-2436666-A2 | METHOD FOR OBTAINING NOVEL DERIVATIVES OF NAPHTALENE FOR THE IN VIVO DIAGNOSIS OF ALZHEIMER 'S DISEASE | Centro De Neurociencias De Cuba (CU) | 2012-04-04 | — | — | EP | disclosed |