Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568601 | 0.91 | NR1I2 (0.35) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL9542136 | 0.87 | CA2 (0.36) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL9615906 | 0.85 | HTT (0.43) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL600325 | 0.83 | ALDH1A1 (0.36) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL2074919 | 0.82 | HTT (0.35) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL644415 | 0.81 | CYP1A2 (0.36) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL17417188 | 0.80 | HTT (0.54) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL9101581 | 0.80 | HTT (0.43) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL10954377 | 0.80 | HTT (0.34) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL28564255 | 0.80 | LMNA (0.42) | HTTSNCAALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2579377-B1 | NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME | UBE INDUSTRIES (JP) | 2014-09-03 | — | — | EP | claimed |
| EP-0542497-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |