Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904034 | 0.92 | DRD4 (0.42) | DRD4ACHEMAOBSLC6A12SLC6A13 | |
| SCHEMBL8712887 | 0.83 | ITGB3 (0.58) | DRD4ITGB3ITGA2BRAB9A | |
| SCHEMBL8905696 | 0.82 | TAS1R3 (0.44) | DRD4ACHEKCNH2MCHR1RAB9A | |
| SCHEMBL8903569 | 0.81 | RAB9A (0.41) | ACHEPTGER4RAB9A | |
| SCHEMBL8903566 | 0.81 | RAB9A (0.41) | ACHEPTGER4RAB9A | |
| SCHEMBL8904718 | 0.80 | RAB9A (0.40) | ITGB3ITGA2BPTGER4RAB9A | |
| SCHEMBL8904717 | 0.80 | RAB9A (0.40) | ITGB3ITGA2BPTGER4RAB9A | |
| SCHEMBL8715772 | 0.80 | ACHE (0.45) | DRD4ACHEMAOBSLC6A12SLC6A13 | |
| SCHEMBL8904935 | 0.78 | RAB9A (0.38) | ACHEPTGER4KCNH2RAB9A | |
| SCHEMBL8712906 | 0.78 | TP53 (0.46) | MAOBITGB3ITGA2BPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |