Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904034 | 0.92 | DRD4 (0.42) | KDM4EALDH1A1HPGDLMNAACHE | |
| SCHEMBL8715598 | 0.90 | TPSAB1 (0.51) | TAS1R3TAS1R1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8715772 | 0.87 | ACHE (0.45) | TAS1R3TAS1R1KDM4EALDH1A1HPGD | |
| SCHEMBL8905175 | 0.82 | DRD4 (0.45) | ACHERAB9ADRD4KCNH2MCHR1 | |
| SCHEMBL8903569 | 0.79 | RAB9A (0.41) | TAS1R3TAS1R1KDM4EALDH1A1HPGD | |
| SCHEMBL8903566 | 0.79 | RAB9A (0.41) | TAS1R3TAS1R1KDM4EALDH1A1HPGD | |
| SCHEMBL8712887 | 0.77 | ITGB3 (0.58) | TPSAB1TPSD1TPSG1RAB9ANPC1 | |
| SCHEMBL8714115 | 0.76 | TPSAB1 (0.48) | TAS1R3TAS1R1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8904376 | 0.76 | TPSAB1 (0.48) | TAS1R3TAS1R1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8717837 | 0.75 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |