Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905304 | 0.90 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL8905128 | 0.87 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1NOTUMNPSR1PKM | |
| SCHEMBL26103579 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TDP1NOTUMNPSR1 | |
| SCHEMBL8905262 | 0.76 | MTNR1A (0.41) | ALDH1A1L3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL8904624 | 0.74 | NOTUM (0.50) | ALDH1A1L3MBTL1MEN1KMT2ANOTUM | |
| SCHEMBL25263139 | 0.73 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TDP1NOTUMNPSR1 | |
| SCHEMBL26102775 | 0.73 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TDP1NOTUMNPSR1 | |
| SCHEMBL8905122 | 0.71 | MTNR1A (0.44) | L3MBTL1MEN1KMT2AACEPOLB | |
| SCHEMBL7831498 | 0.71 | POLB (0.56) | ALDH1A1L3MBTL1MEN1KMT2ANOTUM | |
| SCHEMBL8905311 | 0.70 | L3MBTL1 (0.33) | L3MBTL1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616586-A | Tricyclic quinoxalinediones | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| WO-1993008188-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-04-29 | — | — | WO | disclosed |