Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905306 | 0.87 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1NOTUMNPSR1PKM | |
| SCHEMBL8905122 | 0.83 | MTNR1A (0.44) | L3MBTL1TSHRACEPOLB | |
| SCHEMBL8905262 | 0.82 | MTNR1A (0.41) | ALDH1A1L3MBTL1NOTUMNPSR1PKM | |
| SCHEMBL8904624 | 0.79 | NOTUM (0.50) | ALDH1A1L3MBTL1NOTUMNPSR1PKM | |
| SCHEMBL8905304 | 0.77 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1NOTUMNPSR1LMNA | |
| SCHEMBL7831498 | 0.75 | POLB (0.56) | ALDH1A1L3MBTL1NOTUMLMNATSHR | |
| SCHEMBL6195732 | 0.74 | POLB (0.57) | TSHRSMN1; SMN2ACEPOLBNPC1 | |
| SCHEMBL11756352 | 0.74 | MTNR1A (0.48) | ALDH1A1L3MBTL1NOTUMLMNASMN1; SMN2 | |
| SCHEMBL8904589 | 0.73 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1NOTUMNPSR1LMNA | |
| SCHEMBL5740568 | 0.73 | SMN1; SMN2 (0.49) | ALDH1A1L3MBTL1NOTUMLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616586-A | Tricyclic quinoxalinediones | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0642508-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993008188-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-04-29 | — | — | WO | disclosed |