Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905804 | 0.94 | KDM4E (0.40) | KDM4EALDH1A1GAAPKMRAB9A | |
| SCHEMBL8907613 | 0.93 | AGTR1 (0.37) | KDM4EALDH1A1GAAPKMRAB9A | |
| SCHEMBL8906812 | 0.91 | ALDH1A1 (0.39) | KDM4EALDH1A1GAAPKMRAB9A | |
| SCHEMBL8905214 | 0.90 | PPARG (0.37) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL8905630 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1GAAPKMRAB9A | |
| SCHEMBL8906411 | 0.84 | GPR119 (0.38) | LMNAMEN1KMT2APDE4APDE4D | |
| SCHEMBL8905647 | 0.83 | CYP1A2 (0.33) | HPGDPPARG | |
| SCHEMBL8907533 | 0.82 | CYP3A4 (0.34) | CYP3A4CYP2C9AGTR1PPARG | |
| SCHEMBL8905755 | 0.82 | AGTR1 (0.33) | HPGDAGTR1AGTR2 | |
| SCHEMBL8906629 | 0.82 | GPR119 (0.39) | ALDH1A1GAAMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |