SCHEMBL8907295

SCHEMBL8907295

Cc1cc(C)c(CC(=O)NC2(C(=O)O)CCC(C(C)(C)C)CC2)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 8/20 0.35
P2RX7 Q99572 1/20 0.35
PYGL P06737 7/20 0.34
CYP2C9 P11712 1/20 0.32
SHMT1 P34896 2/20 0.32
SHMT2 P34897 2/20 0.32
CXCR5 P32302 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7960146 0.90 S1PR5 (0.35) S1PR5
SCHEMBL7964339 0.89 ALDH1A1 (0.35) S1PR5CYP2C9
SCHEMBL8906013 0.88 P2RX7 (0.34) S1PR5P2RX7
SCHEMBL8907090 0.86 GPR132 (0.37) P2RX7PYGLCYP2C9SHMT1SHMT2
SCHEMBL8907160 0.86 NPC1 (0.40) S1PR5P2RX7
SCHEMBL8907152 0.84 P2RX7 (0.36) P2RX7PYGLCYP2C9SHMT1SHMT2
SCHEMBL8906535 0.83 PYGL (0.34) P2RX7PYGLCYP2C9SHMT1SHMT2
SCHEMBL7964520 0.81 S1PR5 (0.33) S1PR5P2RX7
SCHEMBL8905527 0.81 DRD2 (0.42) PYGLCYP2C9CXCR5
SCHEMBL8905958 0.81 LPAR1 (0.35) P2RX7PYGLCYP2C9SHMT1SHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677449-A PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed
US-5462913-A Pesticides, insecticides, miticides, herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed