Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906233 | 0.87 | MMP2 (0.46) | MMP2MMP9MMP8TP53SMN1; SMN2 | |
| SCHEMBL5557511 | 0.78 | MMP2 (0.54) | MMP2MMP9MMP8TP53SMN1; SMN2 | |
| SCHEMBL8906144 | 0.78 | ALOX5 (0.43) | MMP2MMP9MMP8MAPTF10 | |
| SCHEMBL6317894 | 0.76 | MMP2 (0.48) | MMP2MMP9MMP8TP53SMN1; SMN2 | |
| SCHEMBL6319054 | 0.76 | MMP2 (0.48) | MMP2MMP9MMP8TP53SMN1; SMN2 | |
| SCHEMBL6851850 | 0.76 | FCER2 (0.61) | MMP2MMP9MMP8PYGL | |
| Hydrochloric Acid SCHEMBL5558399 | 0.74 | F10 (0.49) | MMP2MMP9MMP8CTSLCTSS | |
| Hydrochloric Acid SCHEMBL5557656 | 0.74 | F10 (0.49) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL6319686 | 0.74 | MMP2 (0.44) | MMP2MMP9MMP8TP53SMN1; SMN2 | |
| SCHEMBL8906141 | 0.73 | MMP8 (0.55) | MMP2MMP9MMP8TP53CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |