Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906136 | 0.87 | MMP2 (0.47) | MMP2MMP9MMP8SMN1; SMN2TP53 | |
| SCHEMBL8906242 | 0.81 | ALOX5 (0.40) | MMP2MMP9MMP8SMN1; SMN2F10 | |
| SCHEMBL8906770 | 0.76 | CYP19A1 (0.41) | MMP2MMP9MMP8CTSK | |
| SCHEMBL5557511 | 0.76 | MMP2 (0.54) | MMP2MMP9MMP8SMN1; SMN2TP53 | |
| SCHEMBL8906236 | 0.76 | MMP9 (0.55) | MMP2MMP9MMP8SMN1; SMN2TP53 | |
| SCHEMBL28905932 | 0.70 | CYP2A6 (0.54) | SMN1; SMN2TP53RXFP1F10CYP2A6 | |
| SCHEMBL14401103 | 0.70 | CYP2A6 (0.54) | SMN1; SMN2TP53RXFP1F10CYP2A6 | |
| SCHEMBL20976930 | 0.70 | MMP2 (0.52) | MMP2MMP9MMP8SMN1; SMN2TP53 | |
| SCHEMBL14048310 | 0.70 | MMP2 (0.52) | MMP2MMP9MMP8SMN1; SMN2TP53 | |
| SCHEMBL12727418 | 0.70 | MMP2 (0.52) | MMP2MMP9MMP8SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |