Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 9/20 | 0.55 |
| ▸ | MMP2 | P08253 | 5/20 | 0.55 |
| ▸ | MMP9 | P14780 | 5/20 | 0.55 |
| ▸ | PYGL | P06737 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 10/20 | 0.50 |
| ▸ | FCER2 | P06734 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 8/20 | 0.47 |
| ▸ | MMP7 | P09237 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906236 | 0.86 | MMP9 (0.55) | MMP8MMP2MMP9PYGLMMP1 | |
| SCHEMBL8905827 | 0.86 | MMP2 (0.52) | MMP8MMP2MMP9PYGLTP53 | |
| Hydrochloric Acid SCHEMBL5558404 | 0.79 | PARP1 (0.44) | MMP8MMP2MMP9MMP1FCER2 | |
| SCHEMBL6851850 | 0.79 | FCER2 (0.61) | MMP8MMP2MMP9PYGLMMP1 | |
| SCHEMBL15759462 | 0.78 | PSMB5 (0.64) | MMP8MMP2MMP1FCER2MMP3 | |
| SCHEMBL989841 | 0.78 | PSMB5 (0.64) | MMP8MMP2MMP1FCER2MMP3 | |
| SCHEMBL21274301 | 0.77 | TP53 (0.57) | TP53 | |
| SCHEMBL21274299 | 0.77 | TP53 (0.57) | TP53 | |
| SCHEMBL7066966 | 0.76 | MMP1 (0.61) | MMP8MMP2MMP9MMP1FCER2 | |
| SCHEMBL7066963 | 0.76 | MMP1 (0.61) | MMP8MMP2MMP9MMP1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |