Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | VCP | P55072 | 16/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891478 | 0.88 | VCP (0.49) | VCP | |
| SCHEMBL8906961 | 0.88 | NPY5R (0.47) | NPY5RADRA2AMCHR1 | |
| Hydrochloric Acid SCHEMBL8898939 | 0.88 | VCP (0.48) | VCP | |
| SCHEMBL8890197 | 0.84 | PDE5A (0.48) | NPY5RADRA2AVCP | |
| SCHEMBL8889919 | 0.83 | VCP (0.52) | VCP | |
| SCHEMBL8899135 | 0.82 | TRIM58 (0.53) | NPY5RADRA2AVCPMCHR1 | |
| SCHEMBL8891157 | 0.80 | NPY5R (0.54) | NPY5RVCP | |
| SCHEMBL3947713 | 0.80 | ADRA2A (0.69) | NPY5RADRA2AVCPMCHR1 | |
| SCHEMBL8901739 | 0.79 | TAAR1 (0.52) | VCP | |
| SCHEMBL8898260 | 0.79 | VCP (0.50) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |