Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657003 | 0.90 | SHMT1 (0.43) | P2RX7 | |
| SCHEMBL8906519 | 0.89 | KDM4E (0.38) | NPC1RAB9AP2RX7SLC6A2SLC6A4 | |
| SCHEMBL8654468 | 0.89 | SHMT1 (0.38) | NPC1RAB9AP2RX7 | |
| SCHEMBL8906980 | 0.87 | NPC1 (0.41) | NPC1RAB9AP2RX7PSMB5PSMB8 | |
| SCHEMBL7949839 | 0.87 | MEN1 (0.41) | P2RX7KDM4EALDH1A1CXCR5HTT | |
| SCHEMBL8907160 | 0.85 | NPC1 (0.40) | NPC1RAB9AP2RX7PSMB5PSMB8 | |
| SCHEMBL8906515 | 0.85 | P2RX7 (0.41) | NPC1RAB9AP2RX7PSMB5PSMB8 | |
| SCHEMBL8906535 | 0.85 | PYGL (0.34) | P2RX7CXCR5 | |
| SCHEMBL8907439 | 0.83 | NPC1 (0.44) | NPC1RAB9AP2RX7PSMB5PSMB8 | |
| SCHEMBL8907075 | 0.82 | NPC1 (0.39) | NPC1RAB9AP2RX7PSMB5PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |