Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652410 | 0.90 | SHMT1 (0.43) | P2RX7MEN1KMT2AHTTLMNA | |
| SCHEMBL8653109 | 0.89 | SHMT1 (0.39) | NPC1RAB9AP2RX7ATMKMT2A | |
| SCHEMBL8907373 | 0.89 | P2RX7 (0.38) | NPC1RAB9AP2RX7L3MBTL1POLB | |
| SCHEMBL8906980 | 0.88 | NPC1 (0.41) | NPC1RAB9AP2RX7L3MBTL1POLB | |
| SCHEMBL7960093 | 0.87 | MEN1 (0.42) | P2RX7MEN1KMT2AHTTHPGD | |
| SCHEMBL8906515 | 0.86 | P2RX7 (0.41) | NPC1RAB9AP2RX7L3MBTL1POLB | |
| SCHEMBL8907295 | 0.86 | S1PR5 (0.35) | P2RX7S1PR5 | |
| SCHEMBL8907163 | 0.85 | NPC1 (0.39) | NPC1RAB9AP2RX7L3MBTL1POLB | |
| SCHEMBL8907439 | 0.84 | NPC1 (0.44) | NPC1RAB9AP2RX7L3MBTL1POLB | |
| SCHEMBL8907075 | 0.83 | NPC1 (0.39) | NPC1RAB9AP2RX7L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |