Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764679 | 0.90 | NPC1 (0.41) | NPC1RAB9ADRD2DRD4DRD3 | |
| SCHEMBL8906980 | 0.89 | NPC1 (0.41) | NPC1RAB9APSMB8PSMB5MAPT | |
| SCHEMBL8905527 | 0.86 | DRD2 (0.42) | NPC1RAB9ADRD2DRD4DRD3 | |
| SCHEMBL8906515 | 0.84 | P2RX7 (0.41) | NPC1RAB9APSMB8PSMB5P2RX7 | |
| SCHEMBL8907160 | 0.84 | NPC1 (0.40) | NPC1RAB9APSMB8PSMB5P2RX7 | |
| SCHEMBL8907163 | 0.83 | NPC1 (0.39) | NPC1RAB9APSMB8PSMB5ALDH1A1 | |
| SCHEMBL8907075 | 0.81 | NPC1 (0.39) | NPC1RAB9APSMB8PSMB5MAPT | |
| SCHEMBL8906430 | 0.80 | SIGMAR1 (0.49) | ALDH1A1P2RX7 | |
| Bicarbonate SCHEMBL7615733 | 0.79 | LMNA (0.44) | NPC1RAB9ADRD2DRD4DRD3 | |
| SCHEMBL6767273 | 0.79 | NPC1 (0.41) | NPC1RAB9AGRIN2BPSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |