Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359465 | 0.79 | DHODH (0.38) | BRS3 | |
| SCHEMBL6917321 | 0.78 | ABCB11 (0.36) | BRS3AGTR2AGTR1 | |
| SCHEMBL8359460 | 0.77 | ADORA3 (0.38) | BRS3 | |
| SCHEMBL7810318 | 0.74 | — | — | |
| SCHEMBL7808511 | 0.73 | — | — | |
| SCHEMBL8364071 | 0.73 | ADORA3 (0.37) | BRS3AGTR1 | |
| SCHEMBL9491813 | 0.72 | DHODH (0.40) | — | |
| SCHEMBL9304542 | 0.72 | BRS3 (0.56) | BRS3AGTR2AGTR1 | |
| SCHEMBL9302495 | 0.71 | AGTR1 (0.37) | BRS3AGTR2AGTR1 | |
| SCHEMBL8362076 | 0.71 | AGTR2 (0.40) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639773-A | TREATING GLAUCOMA | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |