Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 10/20 | 0.44 |
| ▸ | RARB | P10826 | 10/20 | 0.44 |
| ▸ | RARG | P13631 | 10/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195254 | 0.90 | RARB (0.41) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8907362 | 0.84 | CYP3A4 (0.48) | RARARARBRARGCA12CA1 | |
| SCHEMBL9256097 | 0.78 | CYP3A4 (0.57) | RARARARBRARGCA12CA1 | |
| SCHEMBL7713085 | 0.77 | RARA (0.45) | RARARARBRARGCA12CA1 | |
| SCHEMBL8440028 | 0.76 | RARA (0.54) | RARARARBRARGCA12CA1 | |
| SCHEMBL8908927 | 0.74 | CYP3A4 (0.55) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL10566455 | 0.72 | RARA (0.50) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL7714846 | 0.70 | RARA (0.52) | RARARARBRARGCA12CA1 | |
| SCHEMBL5084222 | 0.70 | CYP3A4 (0.63) | RARARARBRARGCA12CA1 | |
| SCHEMBL20636868 | 0.69 | RARB (0.54) | RARARARBRARGCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |