Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.57 |
| ▸ | RARA | P10276 | 7/20 | 0.52 |
| ▸ | RARB | P10826 | 7/20 | 0.52 |
| ▸ | RARG | P13631 | 7/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193675 | 0.90 | CYP3A4 (0.55) | CYP3A4RARARARBRARGCYP26A1 | |
| SCHEMBL8908796 | 0.87 | CYP3A4 (0.75) | CYP3A4RARARARBRARGCYP26A1 | |
| SCHEMBL8907362 | 0.81 | CYP3A4 (0.48) | CYP3A4RARARARBRARGCYP26A1 | |
| SCHEMBL5419894 | 0.79 | CYP3A4 (0.62) | CYP3A4RARARARBRARGCYP26A1 | |
| SCHEMBL7714846 | 0.79 | RARA (0.52) | CYP3A4RARARARBRARGCYP26A1 | |
| SCHEMBL8907346 | 0.78 | RARA (0.44) | CYP3A4RARARARBRARGCYP26A1 | |
| SCHEMBL8440028 | 0.77 | RARA (0.54) | CYP3A4RARARARBRARGCYP26A1 | |
| SCHEMBL14371956 | 0.76 | CYP3A4 (0.67) | CYP3A4CYP26A1NPC1TP53CYP26B1 | |
| SCHEMBL5184246 | 0.76 | CYP26A1 (0.74) | CYP3A4RARARARBRARGCYP26A1 | |
| SCHEMBL5431263 | 0.76 | CYP3A4 (0.61) | CYP3A4RARARARBRARGCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |