Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907598 | 0.86 | CYP1A2 (0.47) | PPARGPPARA | |
| SCHEMBL8644119 | 0.80 | PPARG (0.47) | PPARGPPARALTA4H | |
| SCHEMBL8640502 | 0.75 | LTA4H (0.43) | ALDH1A1PPARGPPARALTA4H | |
| SCHEMBL8641136 | 0.74 | LTA4H (0.43) | ALDH1A1LTA4HSMN1; SMN2 | |
| SCHEMBL9668337 | 0.73 | ALDH1A1 (0.36) | ALDH1A1NPSR1 | |
| SCHEMBL11154253 | 0.70 | CYP1A2 (0.59) | ALDH1A1NPSR1PPARGPPARASMN1; SMN2 | |
| SCHEMBL8639364 | 0.69 | PPARG (0.44) | ALDH1A1PPARGPPARALTA4H | |
| Propionic Acid SCHEMBL8907700 | 0.68 | ALDH1A1 (0.43) | ALDH1A1NPSR1SCN9AFPR2PPARG | |
| SCHEMBL10879122 | 0.68 | LMNA (0.56) | ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL9633386 | 0.67 | ALDH1A1 (0.58) | ALDH1A1SCN9AFPR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700816-A | ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. | 1997-12-23 | — | — | US | claimed |