Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907689 | 0.77 | SERPINE1 (0.36) | APAF1POLBRAB9APAX8KDM4E | |
| SCHEMBL8907884 | 0.73 | S100A4 (0.36) | APAF1POLBRAB9APAX8KDM4E | |
| SCHEMBL11412083 | 0.73 | ACP3 (0.61) | ACP3POLB | |
| SCHEMBL7185584 | 0.69 | ACP3 (0.47) | ACP3APAF1POLBRAB9AKDM4E | |
| SCHEMBL8909107 | 0.67 | TSHR (0.33) | POLBRAB9AKDM4EALDH1A1 | |
| SCHEMBL8907599 | 0.67 | CYP1A2 (0.38) | POLBRAB9APAX8KDM4EALDH1A1 | |
| SCHEMBL6435923 | 0.67 | ACP3 (0.68) | ACP3 | |
| SCHEMBL8908933 | 0.65 | HTR2C (0.40) | POLBALDH1A1 | |
| SCHEMBL8908407 | 0.64 | ALDH1A1 (0.39) | POLBALDH1A1 | |
| SCHEMBL8908855 | 0.64 | CYP1A2 (0.44) | APAF1POLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682657-B1 | 9H-INDENO[1,2-b]PYRAZINE-3(4H)-ONES AND 9H-INDENO[1,2-b]PYRAZINE-2,3(1H,4H)-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-11-19 | — | — | EP | disclosed |