Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908407 | 0.85 | ALDH1A1 (0.39) | HTR2CHTR2BHTR2AGAAUSP2 | |
| SCHEMBL8908855 | 0.85 | CYP1A2 (0.44) | GAAUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8908279 | 0.80 | RAB9A (0.46) | HTR2CHTR2BHTR2AGAACYP2D6 | |
| SCHEMBL8908448 | 0.80 | ALDH1A1 (0.43) | GAAUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1798685 | 0.77 | CYP1A2 (0.53) | HTR2CHTR2BHTR2AGAACYP1A2 | |
| SCHEMBL8909181 | 0.76 | HTR2C (0.49) | HTR2CHTR2ACYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL6167962 | 0.75 | CYP1A2 (0.52) | HTR2CHTR2BHTR2AGAACYP1A2 | |
| SCHEMBL6992174 | 0.70 | CYP1A2 (0.46) | HTR2CHTR2BHTR2AUSP2CYP1A2 | |
| SCHEMBL8907689 | 0.69 | SERPINE1 (0.36) | HTR2BCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8907884 | 0.69 | S100A4 (0.36) | TSHRSMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682657-B1 | 9H-INDENO[1,2-b]PYRAZINE-3(4H)-ONES AND 9H-INDENO[1,2-b]PYRAZINE-2,3(1H,4H)-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-11-19 | — | — | EP | disclosed |