Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974200 | 0.84 | KDM4E (0.41) | ADRA1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL2970791 | 0.84 | KDM4E (0.45) | ADRA1AKDM4EALDH1A1 | |
| SCHEMBL3625139 | 0.81 | ADRA1A (0.41) | ADRA1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL8670294 | 0.79 | KDM4E (0.40) | ADRA1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL7544325 | 0.79 | ADRA1A (0.50) | ADRA1AKDM4EALDH1A1HPGDGLA | |
| SCHEMBL7543660 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1HPGDGAATUBB1 | |
| SCHEMBL23758389 | 0.71 | PTGS2 (0.39) | — | |
| SCHEMBL8766176 | 0.71 | SLC6A2 (0.43) | ADRA1AKDM4EALDH1A1HPGDACHE | |
| SCHEMBL7333093 | 0.71 | CA12 (0.41) | KDM4EALDH1A1HPGDACHECA12 | |
| SCHEMBL28484454 | 0.70 | CA2 (0.47) | ADRA1AKDM4EALDH1A1ACHECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900656-B1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2017-05-17 | — | — | EP | disclosed |
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-08-20 | — | — | US | disclosed |
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-08-20 | — | — | US | disclosed |
| US-5612462-A | Process for preparing bridged stereorigid metallocenes | WITCO GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5543535-A | Organotin compounds useful in preparing bridged stereorigid metallocenes | WITCO GMBH (DE) | 1996-08-06 | — | — | US | disclosed |
| US-5474716-A | Process for the preparation of bridged cyclopentadienylmagnesium compounds and use thereof for preparing metallocenes | WITCO GMBH (DE) | 1995-12-12 | — | — | US | disclosed |
| CN-1022250-C | Process for preparing solid catalyst for olefin polymerization | MITSUI PETROCHEMICAL IND (JP) | 1993-09-29 | — | — | CN | disclosed |
| CN-1021446-C | PROCESS FOR PREPARATION OF CATALYST FOR OLEFINE POLYMERIZATION | MITSUI PETROCHEMICAL IND (JP) | 1993-06-30 | — | — | CN | disclosed |
| CN-1021230-C | Process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSLRIE (JP) | 1993-06-16 | — | — | CN | disclosed |
| CN-1070650-A | Bridged metallocene compound, process for producing catalyst component, and process for polymerizing olefin | DSM NV (NL) | 1993-04-07 | — | — | CN | disclosed |
| CN-1017804-B | RANDOM COPOLYMER OF CYCLOOLEFINES AND ITS PROCESS | MITSUI PETROCHEMICAL IND (JP) | 1992-08-12 | — | — | CN | disclosed |
| CN-1039031-A | Solid catalyst for olefin polymerization and method for making thereof | MITSUI PETROCHEMICAL IND (JP) | 1990-01-24 | — | — | CN | disclosed |
| CN-1038820-A | Catalyst for olefines polymerizing and method for making thereof | MITSUI PETROCHEMICAL INUSTRIES (JP) | 1990-01-17 | — | — | CN | disclosed |
| CN-1037715-A | The polymerization process of alkene | MITSUI PETROCHEMICAL IND (JP) | 1989-12-06 | — | — | CN | disclosed |
| CN-88101641-A | Cyclic olefine random copolymers and method for making thereof | — | 1988-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | HAVCR2, SLC10A1, SORD | ADRA1A 1635/4885KDM4E 4762/4885ALDH1A1 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.