SCHEMBL8909068

SCHEMBL8909068

COc1c(C)cc(C)c(Br)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.43
CA4 P22748 6/20 0.43
ALDH1A1 P00352 4/20 0.36
ACHE P22303 1/20 0.36
TSHR P16473 1/20 0.35
PPARG P37231 1/20 0.35
NCOA2 Q15596 1/20 0.35
NCOA1 Q15788 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
CA1 P00915 4/20 0.33
CA6 P23280 4/20 0.33
HPGD P15428 1/20 0.33
AGXT P21549 1/20 0.32
PTPN1 P18031 1/20 0.32
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32
NQO2 P16083 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12552998 0.82 ACHE (0.43) CA2CA4ALDH1A1ACHETSHR
SCHEMBL4046189 0.81 CA2 (0.43) CA2CA4ALDH1A1ACHETSHR
SCHEMBL11344934 0.80 TDP1 (0.41) CA2CA4ALDH1A1HPGDPTPN1
SCHEMBL148267 0.77 ALDH1A1 (0.43) ALDH1A1ACHESMN1; SMN2AGXTPKM
SCHEMBL16302340 0.77 CA2 (0.36) CA2CA4ALDH1A1ACHETSHR
SCHEMBL4209565 0.76 ACHE (0.41) CA2CA4ALDH1A1ACHETSHR
SCHEMBL258754 0.76 CA2 (0.43) CA2CA4ALDH1A1ACHETSHR
SCHEMBL31643870 0.76 CA2 (0.43) CA2CA4ALDH1A1ACHETSHR
SCHEMBL356846 0.76 TSHR (0.40) ALDH1A1TSHRESR2
SCHEMBL13338225 0.75 ACHE (0.39) CA2CA4ALDH1A1ACHESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1067994-C Bisresorcinyltriazines CIBA GEIGY AG (CH) 2001-07-04 CN disclosed
US-5686233-A PHOTOGRAPHIC FILM STABILIZER CIBA-GEIGY CORPORATION (US) 1997-11-11 US disclosed