⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794407 | 0.79 | CASP3 (0.35) | — | |
| SCHEMBL6022461 | 0.76 | — | — | |
| SCHEMBL1286136 | 0.75 | KDM4E (0.33) | — | |
| SCHEMBL11880209 | 0.71 | — | — | |
| SCHEMBL9959060 | 0.71 | — | — | |
| SCHEMBL555854 | 0.68 | GSR (0.43) | — | |
| SCHEMBL11880200 | 0.67 | — | — | |
| SCHEMBL2027730 | 0.67 | ALDH1A1 (0.43) | — | |
| SCHEMBL502220 | 0.67 | MAPT (0.38) | — | |
| SCHEMBL6464295 | 0.67 | AKT1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115382002-B | Sponge dressing with intelligent antibacterial and infection indication functions and preparation method thereof | 东华大学 | 2023-04-07 | — | — | CN | claimed |
| CN-111494315-A | pH and reduction double-sensitive nano micelle and preparation method and application thereof | 广州医科大学附属第二医院 | 2020-08-07 | — | — | CN | claimed |
| CN-109620972-A | A kind of T1-T2 bimodal targeted imaging contrast agent and preparation method for pulmonary cancer diagnosis | 广州创赛生物医用材料有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-105983106-A | IL-13 modified gadolinium chelate containing liposome targeted magnetic resonance imaging contrast agent and preparation method and application thereof | 杨庆宪 | 2016-10-05 | — | — | CN | claimed |
| CN-103582497-A | Polymalic acid based nanoconjugates for imaging | CEDARS SINAI MEDICAL CENTER | 2014-02-12 | — | — | CN | claimed |
| US-20120258049-A1 | POLYMALIC ACID BASED NANOCONJUGATES FOR IMAGING | CEDARS-SINAI MEDICAL CENTER (US) | 2012-10-11 | — | — | US | claimed |
| JP-6336474-A | — | — | None | — | — | JP | disclosed |
| EP-3953367-B1 | VERSATILE PEPTIDE AND PROTEIN MACROCYCLIZATION AND MULTIMERIZATION WITH DIELS-ALDER CYCLOADDITIONS | UNIV CHICAGO (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4600411-A2 | VERSATILE PEPTIDE AND PROTEIN MACROCYCLIZATION AND MULTIMERIZATION WITH DIELS-ALDER CYCLOADDITIONS | The University of Chicago (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20250122240-A1 | Versatile Peptide and Protein Macrocyclization and Multimerization with Diels-Alder Cycloadditions | THE UNIVERSITY OF CHICAGO (US) | 2025-04-17 | — | — | US | disclosed |
| US-12209143-B2 | Versatile peptide and protein macrocyclization and multimerization with diels-alder cycloadditions | THE UNIVERSITY OF CHICAGO (US) | 2025-01-28 | — | — | US | disclosed |
| US-20240016943-A1 | SYNTHETIC DNA BINDING DOMAINS AND USES THEREOF | THE UNIVERSITY OF CHICAGO (US) | 2024-01-18 | — | — | US | disclosed |
| EP-4251642-A1 | SYNTHETIC DNA BINDING DOMAINS AND USES THEREOF | The University of Chicago (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-2694117-A1 | POLYMALIC ACID BASED NANOCONJUGATES FOR IMAGING | Cedars-Sinai Medical Center (US) | 2014-02-12 | — | — | EP | disclosed |
| CN-103582497-A | Polymalic acid based nanoconjugates for imaging | CEDARS SINAI MEDICAL CENTER | 2014-02-12 | — | — | CN | disclosed |
| WO-2012139030-A1 | POLYMALIC ACID BASED NANOCONJUGATES FOR IMAGING | CEDARS-SINAI MEDICAL CENTER (US) | 2012-10-11 | — | — | WO | disclosed |
| US-20120258049-A1 | POLYMALIC ACID BASED NANOCONJUGATES FOR IMAGING | CEDARS-SINAI MEDICAL CENTER (US) | 2012-10-11 | — | — | US | disclosed |
| CN-101918020-A | The IL-4 mutein receptor antagonists of modifying | AEROVANCE INC | 2010-12-15 | — | — | CN | disclosed |
| US-5639579-A | SOLID STATE CAMERAS, LIQUID CRYSTAL DISPLAYS | TOYO GOSEI KOGYO CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| JP-H06336474-A | FLUOROALKYL GROUP-CONTAINING MALEIMIDE DERIVATIVE | NIPPON OIL & FATS CO LTD | 1994-12-06 | — | — | JP | disclosed |