Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8266944 | 0.87 | TSHR (0.55) | TP53TSHRHRH3SMN1; SMN2USP2 | |
| SCHEMBL17479229 | 0.85 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1KDM1A | |
| SCHEMBL28067576 | 0.84 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1KDM1A | |
| SCHEMBL26124912 | 0.84 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1KDM1A | |
| SCHEMBL31512292 | 0.84 | L3MBTL1 (0.51) | TPSAB1TPSD1TPSG1TP53TSHR | |
| SCHEMBL12162946 | 0.84 | HRH3 (0.51) | TPSAB1TPSD1TPSG1TP53TSHR | |
| SCHEMBL18505995 | 0.82 | TSHR (0.46) | TP53TSHRHRH3SMN1; SMN2USP2 | |
| SCHEMBL5623295 | 0.82 | L3MBTL1 (0.54) | TPSAB1TPSD1TPSG1TP53TSHR | |
| SCHEMBL9363422 | 0.81 | TPSAB1 (0.41) | TPSAB1TPSD1TPSG1TP53TSHR | |
| SCHEMBL4283947 | 0.79 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1HRH3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063148-B1 | AZABENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2020-04-29 | — | — | EP | disclosed |
| EP-3063148-B1 | AZABENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2020-04-29 | — | — | EP | disclosed |
| EP-3063148-A1 | AZABENZIMIDAZOLE DERIVATIVES | Boehringer Ingelheim International GmbH (DE) | 2016-09-07 | — | — | EP | disclosed |
| US-9187477-B2 | Azabenzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-9187477-B2 | Azabenzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-9187477-B2 | Azabenzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| WO-2015063011-A1 | AZABENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-05-07 | — | — | WO | disclosed |
| WO-2015063011-A1 | AZABENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-05-07 | — | — | WO | disclosed |
| US-20150119393-A1 | NEW AZABENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-30 | — | — | US | disclosed |
| US-20150119393-A1 | NEW AZABENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-30 | — | — | US | disclosed |
| US-20150119393-A1 | NEW AZABENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-30 | — | — | US | disclosed |
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | disclosed |
| EP-0684948-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME. | DIAGNOSTIKFORSCHUNG INST (DE) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994019352-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1994-09-01 | — | — | WO | disclosed |
| EP-0447013-B1 | Fluorobenzene sulphonamides | SCHERING AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0263059-B1 | COMPLEXES AMIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0447013-A1 | Fluorobenzene sulphonamides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0413405-A2 | Use of amide complex compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0336879-A1 | Meso-tetraphenylporphyrin complex compounds,process for their preparation and pharmaceuticals containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119393-A1 | NEW AZABENZIMIDAZOLE DERIVATIVES | PRKAR2B, PRKAB2, PRKAB1 | TPSAB1 2957/4885TPSD1 3820/4885TPSG1 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.