Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910208 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL8909618 | 0.73 | SIRT2 (0.37) | C3AR1SIRT2REN | |
| SCHEMBL8908848 | 0.65 | F2R (0.37) | SIRT2REN | |
| SCHEMBL8910552 | 0.63 | REN (0.36) | SIRT2REN | |
| SCHEMBL8910523 | 0.63 | KDM4E (0.38) | SIRT2 | |
| SCHEMBL8909763 | 0.63 | P2RX1 (0.44) | SIRT2REN | |
| SCHEMBL9800494 | 0.63 | P2RX1 (0.44) | SIRT2REN | |
| SCHEMBL8909424 | 0.63 | SIRT2 (0.34) | SIRT2REN | |
| SCHEMBL8910197 | 0.63 | REN (0.36) | SIRT2REN | |
| SCHEMBL9800575 | 0.62 | REN (0.41) | SIRT2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |