Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909624 | 0.83 | C3AR1 (0.31) | — | |
| SCHEMBL8908823 | 0.76 | REN (0.34) | — | |
| SCHEMBL8910706 | 0.75 | F2R (0.38) | TSHR | |
| SCHEMBL8910205 | 0.70 | GPR132 (0.36) | GPR132 | |
| SCHEMBL8909367 | 0.63 | P2RX1 (0.42) | TSHR | |
| SCHEMBL7274989 | 0.62 | P2RX1 (0.31) | — | |
| SCHEMBL8910700 | 0.61 | REN (0.40) | — | |
| SCHEMBL2653136 | 0.61 | C3AR1 (0.48) | ALDH1A1CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL2654203 | 0.60 | MEN1 (0.44) | ALDH1A1CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL8908817 | 0.60 | REN (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |