Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910994 | 0.83 | CYP1A2 (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8910750 | 0.82 | SLC9A1 (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3035282 | 0.73 | CASP6 (0.52) | CASP6ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27189378 | 0.71 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL196831 | 0.71 | HSD17B1 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3563229 | 0.70 | ENPP2 (0.40) | ALDH1A1 | |
| SCHEMBL30274548 | 0.69 | MEN1 (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL197879 | 0.69 | MEN1 (0.44) | ALDH1A1 | |
| SCHEMBL3562296 | 0.69 | ATM (0.39) | — | |
| SCHEMBL15009954 | 0.68 | SCN9A (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5596095-A | REMOVAL OF NEOPENTYL PROTECTING GROUPS AND REGENERATION OF PARENT DRUGS | PROCEPT, INC. (US) | 1997-01-21 | — | — | US | disclosed |
| WO-1996018609-A1 | FORMATION AND UTILITY OF SULFONIC ACID PROTECTING GROUPS | PROCEPT, INC. (US) | 1996-06-20 | — | — | WO | disclosed |