Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909829 | 0.85 | CYP2D6 (0.48) | CYP2D6THPOLMNAPMP22AOC3 | |
| SCHEMBL7861690 | 0.77 | CYP2D6 (0.71) | CYP2D6THPOLMNAPMP22ABCB1 | |
| SCHEMBL19944416 | 0.71 | DRD2 (0.61) | CYP2D6THPOLMNAPMP22SIGMAR1 | |
| SCHEMBL30151910 | 0.69 | HTT (0.65) | LMNAABCB1MEN1KMT2AMAPT | |
| SCHEMBL19944378 | 0.69 | SIGMAR1 (0.49) | CYP2D6THPOLMNAPMP22SIGMAR1 | |
| SCHEMBL7860449 | 0.69 | CYP2D6 (0.67) | CYP2D6THPOLMNAPMP22ABCB1 | |
| SCHEMBL19944866 | 0.69 | PARP1 (0.47) | CYP2D6THPOLMNAPMP22SIGMAR1 | |
| SCHEMBL6021254 | 0.66 | CYP2D6 (1.00) | CYP2D6THPOLMNAPMP22ABCB1 | |
| Hydrochloric Acid SCHEMBL2001258 | 0.65 | LMNA (1.00) | CYP2D6THPOLMNAPMP22ABCB1 | |
| SCHEMBL7862476 | 0.63 | ABCB1 (0.65) | LMNAABCB1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698565-A | TREATMENT OF PSYCHOTIC DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-12-16 | — | — | US | claimed |